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Isolation and Bioinspired Total Synthesis of Rugosiformisin A, A Skeleton-Rearranged Abietane-Type Diterpenoid from Isodon rugosiformis  期刊论文  

  • 编号:
    FB1390D4E1FE5933C3AAE1D4FF03C487
  • 作者:
    Wang, Bin ;Jiang, HuaYi ;Yang, Jin ;Li, Jun ;Yan, BingChao ;Chen, Xi ;Hu, Kun ;Li, XingRen ;Sun, HanDong ;Deng, Jun ;Puno, PemaTenzin
  • 语种:
    英文
  • 期刊:
    CASE REPORTS IN INFECTIOUS DISEASES ISSN:2090-6625 2022 年 2022 卷 ; OCT 22
  • 摘要:

    Rugosiformisin A, a skeleton-rearranged abietanetype diterpenoid with a spiro[4.5]decane motif, was isolated from Isodon rugosiformis. Its structure was unambiguously established via NMR spectroscopic analysis and single-crystal X-ray diffraction. A bioinspired asymmetric synthesis of rugosiformisin A was achieved in 15 steps with 2.7% overall yield. The synthesis features an iridium-catalyzed asymmetric polyene cyclization and a semipinacol rearrangement.

  • 推荐引用方式
    GB/T 7714:
    Wang Bin,Jiang Hua-Yi,Yang Jin, et al. Isolation and Bioinspired Total Synthesis of Rugosiformisin A, A Skeleton-Rearranged Abietane-Type Diterpenoid from Isodon rugosiformis [J].CASE REPORTS IN INFECTIOUS DISEASES,2022,2022.
  • APA:
    Wang Bin,Jiang Hua-Yi,Yang Jin,Li Jun,&Puno Pema-Tenzin.(2022).Isolation and Bioinspired Total Synthesis of Rugosiformisin A, A Skeleton-Rearranged Abietane-Type Diterpenoid from Isodon rugosiformis .CASE REPORTS IN INFECTIOUS DISEASES,2022.
  • MLA:
    Wang Bin, et al. "Isolation and Bioinspired Total Synthesis of Rugosiformisin A, A Skeleton-Rearranged Abietane-Type Diterpenoid from Isodon rugosiformis" .CASE REPORTS IN INFECTIOUS DISEASES 2022(2022).
  • 数据来源自科睿唯安Web of Science核心合集
  • 入库时间:
    2023/1/29 11:42:45
  • 更新时间:
    2023/1/29 11:42:45
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