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CXCL13 in laboratory diagnosis of Lyme neuroborreliosis-the performance of the recomBead and ReaScan CXCL13 assays in human cerebrospinal fluid samples  期刊论文  

  • 编号:
    D834569EDFC29188CD490CF3CBD75116
  • 作者:
    Haglund, Sofie[1,2] Lager, Malin[1,2] Gyllemark, Paula[2,3] Andersson, Garda[1,2] Ekelund, Oskar[4] Sundqvist, Martin[5] Henningsson, Anna J.[1,2,6,7]
  • 语种:
    英文
  • 期刊:
    EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES ISSN:0934-9723 2022 年
  • 疾病分类:
    其它感染性疾病
  • 关键词:
  • 摘要:

    The chemokine CXCL13 is used as complement to serology in the diagnostics of Lyme neuroborreliosis (LNB). We evaluated and compared the semi-quantitative, cassette-based ReaScan CXCL13 assay with the quantitative recomBead CXCL13 assay using a collection of 209 cerebrospinal fluid samples. The categorical agreement between results interpreted as negative, grey zone, and positive by the two methods was 87%. The diagnostic sensitivity was higher using the recomBead assay, whereas specificity was higher using ReaScan. Few manual steps, and a short turn-around time with no batching of samples makes the ReaScan CXCL13 assay an attractive complement to serology in the diagnostics of LNB.

  • 推荐引用方式
    GB/T 7714:
    Haglund Sofie,Lager Malin,Gyllemark Paula, et al. CXCL13 in laboratory diagnosis of Lyme neuroborreliosis-the performance of the recomBead and ReaScan CXCL13 assays in human cerebrospinal fluid samples [J].EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES,2022.
  • APA:
    Haglund Sofie,Lager Malin,Gyllemark Paula,Andersson Garda,&Henningsson Anna J..(2022).CXCL13 in laboratory diagnosis of Lyme neuroborreliosis-the performance of the recomBead and ReaScan CXCL13 assays in human cerebrospinal fluid samples .EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES.
  • MLA:
    Haglund Sofie, et al. "CXCL13 in laboratory diagnosis of Lyme neuroborreliosis-the performance of the recomBead and ReaScan CXCL13 assays in human cerebrospinal fluid samples" .EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES(2022).
  • 数据来源自科睿唯安Web of Science核心合集
  • 入库时间:
    2021/12/5 23:54:47
  • 更新时间:
    2021/12/5 23:54:47
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