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Development and Pilot of an Mpox Severity Scoring System  期刊论文  

  • 编号:
    66E7F27B455E06AFECA5B434EA561815
  • 作者:
    Zucker, Jason[1];Mclean, Jacob[1]Huang, Simian[1];Delaurentis, Clare[1];Gunaratne, Shauna[1];Stoeckle, Kate[2];Glesby, Marshall J.[2]Wilkin, Timothy J.[2]Fischer, William[3];Damon, Inger[4];Brooks, John T.[4]
  • 语种:
    英文
  • 期刊:
    JOURNAL OF INFECTIOUS DISEASES ISSN:0022-1899 2024 年 229 卷 (S229 - S233) ; MAR 26
  • 关键词:
  • 摘要:

    Clinical severity scores facilitate comparisons to understand risk factors for severe illness. For the 2022 multinational monkeypox clade IIb virus outbreak, we developed a 7-item Mpox Severity Scoring System (MPOX-SSS) with initial variables refined by data availability and parameter correlation. Application of MPOX-SSS to the first 200 patients diagnosed with mpox revealed higher scores in those treated with tecovirimat, presenting >3 days after symptom onset, and with CD4 counts <200 cells/mm(3). For individuals evaluated repeatedly, serial scores were concordant with clinical observations. The pilot MPOX-SSS demonstrated good discrimination, distinguished change over time, and identified higher scores in expected groups.

  • 推荐引用方式
    GB/T 7714:
    Zucker Jason,Mclean Jacob,Huang Simian, et al. Development and Pilot of an Mpox Severity Scoring System [J].JOURNAL OF INFECTIOUS DISEASES,2024,229:S229-S233.
  • APA:
    Zucker Jason,Mclean Jacob,Huang Simian,Delaurentis Clare,&Brooks John T..(2024).Development and Pilot of an Mpox Severity Scoring System .JOURNAL OF INFECTIOUS DISEASES,229:S229-S233.
  • MLA:
    Zucker Jason, et al. "Development and Pilot of an Mpox Severity Scoring System" .JOURNAL OF INFECTIOUS DISEASES 229(2024):S229-S233.
  • 数据来源自科睿唯安Web of Science核心合集
  • 入库时间:
    2024/10/25 9:35:11
  • 更新时间:
    2024/10/25 9:35:11
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